Thursday, February 9, 2023

Kovid’s nasal vaccine is different from other vaccines, know what are its benefits

Covid nasal vaccine: Scientists believe that the nasal vaccine can prove to be a game changer in fighting the corona virus and its many variants. This will create strong immunity against Kovid.

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Nasal vaccine: around the world again COVID-19 A boom is being seen in the cases, India has approved another vaccine to fight this virus. On December 23, 2022 (Friday), the Union Health Ministry haswater vaccine iNCOVACC has been approved for use as a heterologous booster. Health Minister Dr. Mansukh Mandaviya said that Bharat Biotech’s nasal vaccine has been approved and it will be added to the CoWIN app.

First of all, this vaccine will be available in private hospitals. It will be included in the Kovid-19 vaccination program from today.

How does iNCOVACC work?

It is a vector, needleless, intranasal covid vaccine. An intranasal vaccine stimulates a broad immune response through IgG, mucosal IgA, and neutralizing T cell responses.

The science ministry said, “The vaccine has the dual advantage of rapid development of variant-specific vaccines and easy nasal delivery, which will enable large-scale vaccination to protect against emerging variants. It assures to play an important role in mass vaccination during pandemic and endemic.

Nasal vaccine can prove to be a game changer

Scientists believe that the nasal vaccine can prove to be a game changer in fighting the corona virus and its many variants. IIT professor M Vidyasagar, head of the National Covid Supermodel Committee, told News9, “Most vaccines as I understand it do not prevent the accumulation of virus in the nasal passages. They only prevent the accumulation of the virus in the lungs. This is the reason why people can still spread the virus even if they have been vaccinated. There are reasons to believe that an intranasal vaccine may prove more beneficial.” He said that most research on SARS-CoV-2 and our immune system has ignored mucosal immunity in favor of systemic immunity which may be a wrong approach.

Epidemiologist Dr. Chandrakant Lahariya agrees with this. He said, “There are high expectations from the nasal vaccine. The advantage of intranasal vaccines is that they provide local immunity and will also help in reducing transmission to a great extent. We also need to pay attention to the fact that the vaccine should be introduced as soon as possible for small children and newborns. An intranasal vaccine will work best for this age group. It is non-injectable and easy to use.

Many micro-organisms like corona virus enter the body through the mucosa which infects the cells and molecules of the nose, mouth, lungs and digestive tract. Mumbai-based head of infectious diseases Dr Om Srivastava said, “It is the difference between an intramuscular vaccine and an intranasal one. Older vaccines are not successful in triggering an immune response from the mucosa and are forced to rely on immune cells mobilized from elsewhere in the body that arrive at the site of infection. This takes time, and by then the virus can spread and even develop into a serious disease. The nasal vaccine may work faster and better.”

easy to put on

“The intranasal vaccine has two advantages over the intramuscular vaccine,” said Satyajit Rath, immunologist at the Indian Institute of Science Education and Research (IISER), Pune.

“The first is that they are easy to give because they do not need to be injected. The second, which is being widely discussed, is that it is capable of providing better immediate local protection of the nose, throat and lungs.

Immunologist Vinita Bal agreed, adding that the intranasal vaccine should produce antibodies locally, ie in the upper respiratory tract, which is the entry point for SARS-CoV2. If this happens, the virus will be neutralized as soon as it enters and it will not get a chance to spread in the cells.

Vinita Bal said that the intranasal vaccine is easy to use, so it will be easy to implement on a large scale. He said, “Take the example of the oral polio vaccine. Because it is not given through syringes, then the fear of it in the minds of the people can also be reduced.

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